Studies - Goba.eu

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Novel Medicinal Mushroom Blend as a Promising Supplement in Integrative Oncology: A Multi-Tiered Study using 4T1 Triple-Negative Mouse Breast Cancer Model

A great deal of progress has been made in the early detection and treatment of BC; thus, the survival has steadily increased in recent years, reaching the five-year relative survival rate at about 89% of the cases. However, not all patients benefited from those progresses, since the lack of effective treatments against metastasis is still […]

Dietary Supplementation of Hericium erinaceus Increases Mossy Fiber-CA3 Hippocampal Neurotransmission and Recognition Memory in Wild-Type Mice

Hericium erinaceus (Bull.) Pers. is a medicinal mushroom capable of inducing a large number of modulatory effects on human physiology ranging from the strengthening of the immune system to the improvement of cognitive functions. In mice, dietary supplementation with H. erinaceus prevents the impairment of spatial short-term and visual recognition memory in an Alzheimer model. Intriguingly other […]

The use of spent brewery grains for Pleurotus ostreatus cultivation and enzyme production

The best substrate mixture for P. ostreatus mycelium growth comprised 30 % wheat bran (WB), 68 % beech sawdust (BS) and 2 % CaCO3. On the substrates containing SBG, the fastest mycelium growth was observed on the substrate composed of 10 % SBG, 20 % WB, 68 % BS and 2 % CaCO3. According […]

Cultivation Techniques and Medicinal Properties of Pleurotus spp

The aim of this study was to determine the effect of four different fungal extracts (Ganoderma lucidum – GL, Hericium erinaceus – HE, Inonotus obliquus – IO, and Trametes versicolor – TV) on the survival rate, activities of metabolic markers (ALP, ALT, and AST) and antioxidant enzyme activities (CAT, GPx, GST, and SOD), and TAC levels in A. m. carnica.

Fungal extracts influence lifespan and immune responses in the Carniolan honey bee

Influence of Olive Oil Press Cakes on Shiitake (Lentinus edodes) Fruiting Bodies Production and Effect of their Crude Polysaccharides on CCRF-CEM Cell Proliferation

In this study, we observed a negative effect of OOPC (Olive Oil Press Cakes) added to the substrate on mycelial growth and fruiting body maturation of Lentinula edodes, as well as a negative correlation between the OOPC and the cytotoxic effect on CCRF-CEM cells (leukemia cells).

Immunomodulating Activities of Cultivated Maitake (Medicinal Mushroom Grifola frondosa) on Peripheral Blood Mononuclear Cells

Grifola frondosa is a culinary-medicinal mushroom that contains several physiologically active compounds, of which polysaccharides, specifically β-glucans, are known to possess immunomodulating properties. Its extracts are studied for application as adjuncts for chemotherapy, and experiments in animal models support the use of this mushroom for cancer treatment.

Cordycepin production by Cordyceps militaris cultivation on spent brewery grains

SBG represent a readily available, low price substrate for cordycepin solid-state production. Here reported concentrations of cordycepin are so far the highest reported concentrations (10.42 mg/g) obtained on solid-state substrates.

Development of Mycelium-PLA Composites for Improved Mechanical Properties and Radiation Shielding Performance

In this study, we present a novel approach to the development of biocomposites, in which dried fungal biomass is used as a reinforcing phase within a polylactic acid (PLA) matrix. PLA serves as the primary matrix, while the mycelium functions as the reinforcement.

Electrochemical Monitoring of Polystyrene Nanoplastics–Fungal Biomass Interactions for Advanced Sensing Applications

Nanoplastics (NPs), ultrafine synthetic polymer particles, are emerging as a concerning class of pollutants due to their high mobility, persistence, and ability to penetrate biological membranes and accumulate within aquatic ecosystems. Their small size facilitates uptake by organisms and integration into food webs, raising concerns over ecological and human health impacts.