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Hericium erinaceus in the management of faecal calprotectin

Calprotectin is a Mn, Ca and Zn-binding protein of the S100-group which has many functions in the cell. It is a major constituent (60% of the soluble ingredients and 5% of the total proteins) of the cytoplasm of neutrophil granulocytes, as well as monocytes and epithelial cells. During inflammation, the leukocytes migrate through the intestinal […]

Hydrolytic and oxidative enzyme production through cultivation of Pleurotus ostreatus on pulp and paper industry wastes

The study was co-funded by: The growth of oyster mushroom (Pleurotus ostreatus) on pulp and paper industry wastes was studied. Specifically, the question was investigated whether solid- state fermentation of P. ostreatus on paper-mill deinking sludge and primary sludge substrates is appropriate for production of enzymes, relevant to the pulp and paper industry. Following […]

Valorisation of deinking sludge as a substrate for lignocellulolytic enzymes production by Pleurotus ostreatus

Disposal of waste sludges produced in large amounts in the pulp and paper industry imposes significant environmental and economical problems. One strategy to address these issues involves revalorization of paper mill sludges by their application as substrates for microbial production of biotechnologically relevant enzymes. The application of lignocellulolytic enzymes in paper, textile and bioenergy industries is encouraged in order to decrease chemicals and energy consumptions. In […]

Comparison of lovastatin, citrinin and pigment production of different Monascus purpureus strains grown on rice and millet

Six Monascus purpureus (red mould) strains were cultivated on brown rice and millet as substrates. They underwent strain selection for high lovastatin and pigment production, and low citrinin mycotoxin production, with particular reference to potential for millet as substrate. For most of these strains, substrate dry matter loss was 54–60% on rice and 46–48% on […]

Culture Degeneration Reduces Sex-Related Gene Expression, Alters Metabolite Production and Reduces Insect Pathogenic Response in Cordyceps militaris

The study “Culture Degeneration Reduces Sex-Related Gene Expression, Alters Metabolite Production and Reduces Insect Pathogenic Response in Cordyceps militaris” investigates how long-term laboratory subculturing of Cordyceps militaris affects its biological activity, metabolism, and ability to produce important bioactive compounds. The researchers found that repeated subcultivation on artificial media gradually led to culture degeneration. Degenerated cultures […]

Cultivation Technologies for Production of Medicinal Mushroom Biomass: Review

The review study Cultivation Technologies for Production of Medicinal Mushroom Biomass: Review highlights that medicinal mushrooms represent an important source of bioactive compounds with significant potential for use in food supplements, functional foods, veterinary applications, and the pharmaceutical industry. Due to the growing interest in medicinal mushrooms, researchers are increasingly developing various cultivation technologies that […]

Photoregulation of the biosynthetic activity of the edible medicinal mushroom Lentinula edodes in vitro

The findings of the study demonstrate the impact of low-intensity laser and quasi-monochromatic light on the biosynthetic activity of the edible medicinal fungus L. edodes during submerged cultivation. An artificial lighting installation based on matrices of light-emitting diodes (LED) emitting light at 470 nm (blue), 530 nm (green), 650 nm (red), and argon gas laser (488 nm) was used. […]

Characterization, In Vitro Biological Activity and In Vivo Cardioprotective Properties of Trametes versicolor (L.:Fr.) Quél. Heteropolysaccharides in a Rat Model of Metabolic Syndrome

The present study aimed to examine the biological activity and cardioprotective potential of Trametes versicolor heteropolysaccharides (TVH) in a rat model of metabolic syndrome (MetS). This study included 40 Wistar rats divided into 5 groups: CTRL—healthy non-treated rats; MetS—non- treated rats; and H-TV, M-TV and L-TV-rats with MetS treated with either 300, 200 or 100 […]

Bioactive metabolites isolated from Hericium erinaceus (Bull.) Pers.

Research was funded by Our research focus on the isolation of a diverse range of bioactive compounds from employing conventional crhomatographic techniques, followed by their structural characterization predominantly through nuclear magnetic resonance (NMR) spectroscopy. Hericene A was isolated from the ethyl acetate extract of the H. erinaceus fruiting bodies by performing gravitational chromatography, followed by […]

Two-Dimensional Chromatographic Isolation of High Purity Erinacine A from Hericium erinaceus

A simple and robust two-dimensional chromatographic fractionation protocol for the isolation of the neuroprotective compound erinacine A from Hericium erinaceus is proposed. This production platform yielded 19.4 mg of erinacine A from approximately 130 g of mushroom material, with a chromatographic purity of 97.4%. The procedure includes extraction, concentration, fractionation, purification, and characterisation of the […]